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Von Hippel-Lindau disease and endolymphatic sac tumors

✍ Scribed by Mitchell J Ramsey; Mark J Syms; Michael R Holtel

Book ID: 117404375
Publisher: SAGE Publications
Year: 1999
Tongue: English
Weight: 107 KB
Volume: 121
Category: Article
ISSN: 0194-5998
DOI: 10.1016/s0194-5998(99)80523-3

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## Abstract Von Hippel‐Lindau (VHL) disease is an uncommon, autosomal dominant hereditary multitumor syndrome caused by germline alterations of the __VHL__ gene, which has been cloned recently and identified as a tumor suppressor gene. The major lesions in VHL disease include hemangioblastomas in t