Volumes of normal ovaries, ovaries with benign lesions, and ovaries with cancer in menopausal women: Is there an optimal cut-off value to predict malignancy?
✍ Scribed by Rami Aviram; Gilad Gassner; Ofer Markovitch; Ilan Cohen; Ami Fishman; Ronnie Tepper
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 173 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0091-2751
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✦ Synopsis
Abstract
Purpose:
To evaluate different ovarian volume cut‐off values to distinguish between normal ovaries, benign lesions, and malignant lesions in menopausal women.
Methods:
Transvaginal sonographic ovarian volume measurements were performed in 362 menopausal patients prior to gynecologic surgery. Based on the histopathologic results, a total of 466 ovaries were divided into 3 groups: normal ovary, benign lesion, and malignant tumor. Different ovarian volume cut‐off values were analyzed via receiver operating characteristic curves to determine the optimal cut‐off value.
Results:
The mean ovarian volumes in the normal ovary, benign lesion, and malignant tumor groups were 3.4 ± 2.2 cm^3^ (range, 0.6–9.6 cm^3^), 102 ± 308 cm^3^ (range, 0.3–3543 cm^3^), and 368 ± 1176 cm^3^ (range, 8.1–9908) cm^3^, respectively. Cut‐off values of 8 cm^3^ and 10 cm^3^ to distinguish between malignant and nonmalignant lesions had a sensitivity of 100% and 97% and a specificity of 39% and 45%, respectively.
Conclusion:
In menopausal patients, any ovary with a volume >8 cm^3^ can potentially harbor a cancer. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2008