Volume regulation and basolateral co-transport of sodium, potassium, and chloride ions in frog skin epithelium
โ Scribed by Hans H. Ussing
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 646 KB
- Volume
- 405
- Category
- Article
- ISSN
- 0031-6768
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## NINE FIGURES This paper deals with (1) the production of a hydrogen ion gradient across the isolated frog skin, (2) the relationship between the gradient and the active transport of sodium ion, and (3) the effect of potassium ion and aearation on the hydrogen ion gradient and the transport proc
The effect of papaverine, an inhibitor of the phosphodiesterase responsible for breakdown of cAMP, on the transepithelial sodium transport across the isolated frog skin was investigated. Serosal addition of papaverine caused initially an increase in the short-circuit current (SCC), a doubling of the