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Volume increase in growth plate chondrocytes during hypertrophy: the contribution of organic osmolytes

✍ Scribed by C.E Farnum; R Lee; K O’Hara; J.P.G Urban

Book ID
117807588
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
242 KB
Volume
30
Category
Article
ISSN
8756-3282

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The osmotic sensitivity of rat growth pl
The osmotic sensitivity of rat growth plate chondrocytes in situ; clarifying the mechanisms of hypertrophy
✍ Peter G. Bush; Constantinos A. Parisinos; Andrew C. Hall 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB

## Abstract Bone elongation is predominantly driven by the volume expansion of growth plate chondrocytes. This mechanism was initially believed to be “hypertrophy”, describing a proportional increase of cell water and organelles. However, morphometrical analysis subsequently assumed the increase to