✦ LIBER ✦

Voltammetric Determination of Trace Antiepileptic Gabapentin with a Silver-Nanoparticle Modified Multiwalled Carbon Nanotube Paste Electrode

✍ Scribed by Abdollah Yari; Fatemeh Papi; Said Farhadi

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 704 KB
Volume: 23
Category: Article
ISSN: 1040-0397
DOI: 10.1002/elan.201100454

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

For the first time, a novel carbon nanotube bed electrode impregnated with silver–nanoparticles (AgNPs) for the determination of trace amounts of gabapentin (GBP) is described. We synthesized the AgNPs via a new procedure. The voltammetric behavior of the electrode was investigated by cyclic voltammetry. There were linear relationships in the ranges from 3.1×10^−9^ to 2.9×10^−2^ M and from 1.0×10^−8^ to 1.0×10^−2^ GBP with square wave and differential pulse voltammetric peak currents, respectively. The detection limits were 5.6×10^−10^ and 9.7×10^−9^ M, respectively. The electrode showed excellent response over a period of 2 months and was successfully applied in human plasma and pharmaceutical capsular products.

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