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Voltammetric Behavior of Antileukemia Drug Glivec. Part III: In Situ DNA Oxidative Damage by the Glivec Electrochemical Metabolite

✍ Scribed by Victor Constantin Diculescu; Marilene Vivan; Ana Maria Oliveira Brett


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
122 KB
Volume
18
Category
Article
ISSN
1040-0397

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Voltammetric Behavior of Antileukemia Dr
✍ Victor Constantin Diculescu; Marilene Vivan; Ana Maria Oliveira Brett 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB

## Abstract Glivec is a newly developed drug that belongs to the class of 2‐phenylaminopyrimidine. It is a potent inhibitor of __ABL__‐kinase, the main clinical manifestation of chronic myelogenous leukemia (CML). Based on its activity on CML, glivec is undergoing extensive evaluation for its activ