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Voltage-gated sodium channel expression and function in injured and uninjured sensory ganglia neurons

โœ Scribed by B. Moyer; R. Yin; D. Liu; M. Chhoa; C. Li; Y. Luo; M. Zhang; S. Lehto; D. Immke


Book ID
116682006
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
32 KB
Volume
13
Category
Article
ISSN
1528-8447

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## Abstract Peripheral nerve injury induces changes in the level of gene expression for sodium channels Nav1.3, Nav1.8, and Nav1.9 within dorsal root ganglion (DRG) neurons, which may contribute to the development of hyperexcitability, ectopic neuronal discharge, and neuropathic pain. The mechanism