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Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca2+ and Mg2+

✍ Scribed by Won-Kyung Ho; Injune Kim; Chin O. Lee; Yung E. Earm


Book ID
111118273
Publisher
Cambridge University Press
Year
1998
Tongue
English
Weight
452 KB
Volume
507
Category
Article
ISSN
0022-3751

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An unusual inward current which is slowly elicited in the Xenopus oocyte membrane during sustained depolarization is reportedly carried by Na Ο© . It is thought that Na Ο© selective channels are in some way induced to become voltagesensitive by the depolarization. Earlier studies report that the induc