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Voltage dependence of transient and steady currents generated by the Na/K pump in cardiac cells

✍ Scribed by D.C. Gadsby; M. Nakao; A. Bahinski

Book ID
115981769
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
99 KB
Volume
22
Category
Article
ISSN
0022-2828

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πŸ“œ SIMILAR VOLUMES

Voltage dependence of transient and stea
Voltage dependence of transient and steady-state Na/K pump currents in myocytes
✍ David C. Gadsby; Masakazu Nakao; Anthony Bahinski πŸ“‚ Article πŸ“… 1989 πŸ› Springer 🌐 English βš– 460 KB

Experiments are reviewed here in which Na/K pump current was determined as strophanthidin-sensitive current in guinea-pig ventricular myocytes, voltage-clamped and internally-dialyzed via wide-tipped pipettes. In the presence of 150 mM extracellular [Na], both outward and inward pump current, during

Inward-directed current generated by the
Inward-directed current generated by the Na+,K+ pump in Na+- and K+-free medium
✍ Athina Efthymiadis; JΓΌrgen Rettinger; Wolfgang Schwarz πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 445 KB

## Abstract In Na^+^‐ and K^+^‐free solution, an inward‐directed current can be detected in Xenopus oocytes, which is inhibited by cardic glycosides and activated by ATP. Therefore, it is assumed to be generated by the Na^+^, K^+^ pump. At negative membrane potentials, the pump current increases wi