Voltage-activated and odor-modulated conductances in olfactory neurons ofDrosophila melanogaster

✍ Scribed by Dubin, Adrienne E. ;Harris, Greg L.

• Book ID: 101263071
• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 294 KB
• Volume: 32
• Category: Article
• ISSN: 0022-3034
• DOI: 10.1002/(sici)1097-4695(199701)32:1<123::aid-neu11>3.0.co;2-l

✦ Synopsis

Voltage-activated currents and odorsensillar development. The character of odor-induced modulated conductances were studied in cells in semiresponses was more profound and complex later in intact Drosophila third antennal segments (the main development; small, tonic increases in firing frequency olfactory organ) using patch-clamp techniques. All were observed at pupal stages P8 through P11(ii), neurons expressed outward currents, and most exwhile in older pupae and young adults Ç25% of the pressed labile fast transient inward currents with kiincreased responses were phasic-tonic. The apical dennetics similar to Na / currents in other systems. Action drite was the site of odor modulation in Ç90% and potentials were detected as bipolar capacitative cur-100% of responsive adult and early pupal neurons, rent transients in cell-attached or loose patches from respectively. Whole-cell recordings revealed that apthe soma of both odor-sensitive (97%) and insensitive parent nonselective cation and chloride conductances neurons. A mixture of odorants from five chemical were modulated by a mixture of odorants in separate classes caused an increase (Ç70%), decrease antennal neurons.