vOH and pKa values of para substituted tetrafluorobenzoic acids
β Scribed by M.T. Ryan; K.J. Berner
- Book ID
- 113372216
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- English
- Weight
- 221 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1386-1425
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## 3. VIII.92) (o-Hydroxypheny1)methylphosphonic acids are readily obtained from o-(bromomethy1)or o-(hydroxy-methy1)phenols and trialkyl phosphites. Subsequent hydrolysis leads to the corresponding phosphonic acids. For a series of such compounds, the pK, values have been determined by potentiomet
suggested that product inhibition (including cross-product inhibition) of drug biotransformation processes may be due to an interaction of the inhibitory agents with cytochrome P-450 (8,14). Specifically, a competition between the hydroxylated metabolite and the drug for binding sites on cytochrome