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Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery

✍ Scribed by Jing Ni; Ming Chen; Yu Zhang; Rongshan Li; Jiaoti Huang; Shuyuan Yeh


Book ID
117053064
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
244 KB
Volume
300
Category
Article
ISSN
0006-291X

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## Abstract 2‐Methoxyestradiol (2‐ME), an endogenous metabolite of 17β‐estradiol, is present in human blood and urine. Here we show for the first time that 2‐ME significantly inhibited the growth of normal prostate epithelial cells and androgen‐dependent LNCaP and androgen‐independent DU145 prostat