The nitrogen mustard melphalan activates
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Camilla Österlund; Bo Lilliehöök; Barbro Ekstrand-Hammarström; Thomas Sandström;
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Article
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2005
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John Wiley and Sons
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English
⚖ 303 KB
To investigate how respiratory epithelial cells react to an alkylating agent, we exposed human bronchial (BEAS-2B) and alveolar (A549) cells to the nitrogen mustard derivative melphalan. The BEAS-2B cells were highly sensitive to melphalan, as shown by a reduced viability after a 10-min incubation w