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Vitamin D3 potentiates the antitumorigenic effects of arsenic trioxide in human leukemia (HL-60) cells

✍ Scribed by Rogers, Christian S; Yedjou, Clement G; Sutton, Dwayne J; Tchounwou, Paul B


Book ID
125405243
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
378 KB
Volume
3
Category
Article
ISSN
2162-3619

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## Abstract Arsenic trioxide (ATO) has been recommended for the treatment of refractory cases of acute promyelocytic leukemia (APL). Recent studies in our laboratory indicated that oxidative stress plays a key role in ATO‐induced cytotoxicity in human leukemia (HL‐60) cells. In the present investig