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Vitamin D Reduces Musculoskeletal Pain After Infusion of Zoledronic Acid for Postmenopausal Osteoporosis

✍ Scribed by Antonino Catalano; Nancy Morabito; Marco Atteritano; Giorgio Basile; Domenico Cucinotta; Antonino Lasco


Book ID
113023169
Publisher
Springer
Year
2012
Tongue
English
Weight
184 KB
Volume
90
Category
Article
ISSN
1432-0827

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Zoledronic acid (ZOL), a third-generation aminobisphosphonate, showed pronounced antifracture efficacy in a phase III clinical trial [Health Outcomes and Reduced Incidence with Zoledronic Acid Once Yearly-Pivotal Fracture Trial (HORIZON-PFT)] when administered yearly (5-mg infusions of ZOL), produci

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## Abstract Zoledronic acid (ZOL) has shown beneficial effects on bone turnover and bone mineral density (BMD) in postmenopausal osteoporosis. This study compared the efficacy and safety of a once‐yearly i.v. infusion of ZOL with weekly oral alendronate (ALN) in men with osteoporosis. In this multi