Vitamin D metabolite profiles in moderate renal insufficiency of childhood

Expression profiling confirms the role o

Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism

✍ Hilpert, Jan; Wogensen, Lise; Thykjaer, Thomas; Wellner, Maren; Schlichting, Uwe 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 794 KB

## Background: The endocytic receptor megalin constitutes the major pathway for clearance of low-molecular weight plasma proteins from the glomerular filtrate into the renal proximal tubules. furthermore, the receptor has been implicated in a number of other functions in the kidney including uptake