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Vitamin D analogues suppress IGF-I signalling and promote apoptosis in breast cancer cells

โœ Scribed by S.P Xie; G Pirianov; K.W Colston

Book ID
117666853
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
197 KB
Volume
35
Category
Article
ISSN
0959-8049

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The biologically active form of vitamin D 3 , the nuclear hormone 1a,25-dihydroxyvitamin D 3 (VD), is an important regulator of cellular growth, differentiation, and death. The hormone mediates its action through the activation of the transcription factor VDR, which is a member of the superfamily of