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Vitamin D analogs with low affinity for the vitamin D binding protein: Enhanced in vitro and decreased in vivo activity

โœ Scribed by Dr. Roger Bouillon; Katrien Allewaert; Da Zhen Xiang; Biauw Keng Tan; Hugo van Baelen


Book ID
112118796
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
544 KB
Volume
6
Category
Article
ISSN
0884-0431

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The role of the vitamin D-induced calcium binding protein termed calbindin-D (CaBP) in the biological response to 1,25-dihydroxyvitamin D3 was assessed by photoaffinity labeling techniques. The heterobifunctional cross-linking reagent methyl-4-azidobenzoimidate was employed for studies with the 28 K