✦ LIBER ✦
Vitamin B6 and derivatives. II—13C NMR study of systems formed by pyridoxal phosphate or pyridoxal with octopamine
✍ Scribed by Raymond Haran; Jean-Pierre Laurent; Michel Massol; Francoise Nepveu-Juras
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 367 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0749-1581
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Schiff base formation by condensation of pyridoxal phosphate or pyridoxal with octopamine in aqueous or methanolic medium was investigated by ^13^C NMR. Enolimine forms are favoured in methanolic solution, whereas in aqueous solution the predominant ketoenamine forms show a hydrogen bond between the iminium proton and the C‐3‐O^−^ phenolate anion of the pyridoxal phosphate. The addition of Cu^++^ ions is consistent with the hypothesis of chelation of Cu^++^ by the nitrogen of the aldimine function and the phenolate function of pyridoxal phosphate.