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Vitamin B6 analogs. Improved synthesis of 3-hydroxypyridine-4-carboxaldehyde

✍ Scribed by O'Leary, Marion H.; Payne, James R.

Book ID
125538833
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
244 KB
Volume
14
Category
Article
ISSN
0022-2623

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## Abstract The known synthesis of β€œIchiba acid”, 2‐methyl‐3‐hydroxypyridine 4,5‐dicarboxylic acid (VII), starting from ethyl acetylpyruvate and cyanoacetamide, has been reinvestigated and simplified to a five step process. Several derivatives of Ichiba acid have been prepared including the triben