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Vitamin A treatment induces apoptosis through an oxidant-dependent activation of the mitochondrial pathway

✍ Scribed by Fábio Klamt; Felipe Dal-Pizzol; Daniel Pens Gelain; Rodrigo Siqueira Dalmolin; Ramatis Birnfeld de Oliveira; Michele Bastiani; Fabiana Horn; José Cláudio Fonseca Moreira


Book ID
108084543
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
735 KB
Volume
32
Category
Article
ISSN
1065-6995

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## Abstract A20 was originally characterized as a TNF‐inducible gene in human umbilical vein endothelial cells. As an NF‐κB target gene, A20 is also induced in many other cell types by a wide range of stimuli. Expression of A20 has been shown to protect from TNF‐induced apoptosis and also functions