Vital signs and cognitive function are not affected by 23-sodium and 17-oxygen magnetic resonance imaging of the human brain at 9.4 T
✍ Scribed by Ian C. Atkinson; Rachel Sonstegaard; Neil H. Pliskin; Keith R. Thulborn
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 193 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Purpose:
To evaluate the effect of 23‐sodium (^23^Na) and 17‐oxygen (^17^O) magnetic resonance imaging (MRI) at 9.4 (T) on vital signs and cognitive function of the human brain.
Materials and Methods:
Vital sign and cognitive function measurements from healthy volunteers (N = 14) positioned outside and at isocenter of a 9.4 T scanner before and after ^23^Na and ^17^O MRI were compared for changes due to exposure to the static magnetic field and to the gradient switching and radiofrequency radiation during MRI.
Results:
Exposure to the 9.4 T static magnetic field and ^23^Na and ^17^O MRI at 105.92 MHz and 54.25 MHz, respectively, did not have a statistically significant (P > 0.05) effect on the vital signs or cognitive function of healthy normal adults.
Conclusion:
^23^Na and ^17^O MRI of the human brain at 9.4 T does not have any readily demonstrated health risks reflected in vital signs or change in cognitive performance. J. Magn. Reson. Imaging 2010;32:82–87. © 2010 Wiley‐Liss, Inc.