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Visualization of the interaction between archaeal DNA polymerase and uracil-containing DNA by atomic force microscopy

✍ Scribed by Yasuo Asami; Masahiro Murakami; Masatomi Shimizu; Francesca M. Pisani; Isamu Hayata; Takehiko Nohmi


Book ID
108731819
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
242 KB
Volume
11
Category
Article
ISSN
1356-9597

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## Abstract JC polyomavirus (JCV), which infects 90% of the human population, is detectable in human tumors. Its early protein, JCV T‐antigen, transforms cells in vitro and is tumorigenic in experimental animals. Although T‐antigen‐mediated transformation involves genetic alterations of the affecte