✦ LIBER ✦

Visual association encoding activates the medial temporal lobe: A functional magnetic resonance imaging study

✍ Scribed by Serge A.R.B. Rombouts; Willem C.M. Machielsen; Menno P. Witter; Frederik Barkhof; Jaap Lindeboom; Philip Scheltens

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 717 KB
Volume: 7
Category: Article
ISSN: 1050-9631
DOI: 10.1002/(sici)1098-1063(1997)7:6<594::aid-hipo2>3.0.co;2-f

No coin nor oath required. For personal study only.

✦ Synopsis

The involvement of structures in the medial temporal lobe during the encoding of visual associations was studied with functional magnetic resonance imaging. In 11 out of 12 normal healthy volunteers this task resulted in activation in posterior portions of the parahippocampal region, close to the collateral sulcus. In seven subjects activation was encountered in the hippocampal formation. The visual association task as adapted for this study may provide a sensitive measure to study anterograde amnesia prevalent in Alzheimer's disease. Therefore, the present paradigm enables the study of individual changes in learning and memory capacities over time.

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