Visual acuity loss ion rhesus monkey infants fed a taurine-free human infant formula
✍ Scribed by M. Neuringer; J. Sturman
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 500 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0360-4012
No coin nor oath required. For personal study only.
✦ Synopsis
This study examined the effects of dietary taurine severely by dietary taurine deprivation. The rat, for exdeprivation on visual development in rhesus monkeys. ample, appears to have no dietary requirement for taurine From birth to 3 months of age, rhesus monkeys were Sturman 19731, although tissue taurine defed a taurine-free, soy protein-based infant formula, pletion and retinal degeneration can be induced by taurine or the same formula supplemented with taurine. The transport inhibitors such as guanidinoethane sulfonate early postnatal development of visual function was Pasantes-Morales et al, 19831. Howassessed with behavioral measurements of visual ever, there is now evidence that dietary deprivation of acuity.
taurine produces retinal changes in both human children Plasma taurine levels in the taurine-deprived group and infant macaque monkeys. fell to 35-50% of control values, as in human infants fed similar formulas. The visual acuity of the taurinedeprived infants was significantly impaired: acuity thresholds differed from control values by nearly a factor of 2 at 4, 8, and 12 weeks of age. The loss of acuity is associated with morphological changes in photoreceptors, particularly cones in the foveal region.
These results provide direct evidence that taurine is essential for normal visual development in primates, and they support the nutritional importance of taurine for human infants.