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Viscosupplementation with hyaluronic acid in the treatment for cartilage lesions: a review of current evidence and future directions

โœ Scribed by Clegg, Travis E.; Caborn, David; Mauffrey, Cyril


Book ID
120494587
Publisher
Springer
Year
2012
Tongue
English
Weight
284 KB
Volume
23
Category
Article
ISSN
1432-1068

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โœฆ Synopsis


Diseases involving the articular cartilage are one of the leading causes of physical impairment among the adult population. While surgical technique and advancement have allowed us effective means at treating these diseases, this is not without significant risk and morbidity. With a very solid safety profile, viscosupplementation with hyaluronic acid (HA) derivatives has become an excellent modality for treating diseased articular cartilage. Recent literature supports the use of HA not only in the management of the pain associated with osteoarthritis but also as a disease-modifying agent as well. Further studies have started to define exciting new roles for viscosupplementation in the treatment for acute injuries to the joint microenvironment.


๐Ÿ“œ SIMILAR VOLUMES


Hyaluronic acid hydrogel added with ibup
โœ Rolando Barbucci; Milena Fini; Gianluca Giavaresi; Paola Torricelli; Roberto Gia ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 284 KB

## Abstract The effect of hyaluronanโ€based hydrogel with a crossโ€linking degree of 50% (i.e., the amount of carboxylate groups involved in the crossโ€lining reaction) (Hyal 50%), loaded with an antiโ€inflammatory drug (ibuprofenโ€lysine) for local administration in the osteoarthritic knee was evaluate