𝔖 Bobbio Scriptorium
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Visceral lesions in an unusual case of sézary's syndrome

✍ Scribed by F. J. Paradinas; Kathleen M. Harrison

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
717 KB
Volume
33
Category
Article
ISSN
0008-543X

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✦ Synopsis

A 29-year-old woman with long-standing thrombocytopenia due to megakaryocytic hypoplasia developed features of SCzary's syndrome associated with arthropathy and signs of peripheral vascular occlusion. She died 14 months later. At necropsy, cellular infiltrations including lymphocytes, histiocytes, plasma cells, and atypical mononuclear cells were found in the walls of small arteries and parenchyma of visceral organs as well as in the skin. The infiltrations had led to fibrosis and focal parenchymal damage which resembled that seen in experimental and iatrogenic graft-vs.-host reactions. In places there was a transition between these mixed cellular infiltrations and uniformly lymphocytic infiltrations with histologic features of a lymphoma.

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