✦ LIBER ✦

Viruses, protoviruses, development, and evolution

✍ Scribed by Howard M. Temin

Book ID: 102877484
Publisher: John Wiley and Sons
Year: 1982
Tongue: English
Weight: 823 KB
Volume: 19
Category: Article
ISSN: 0730-2312
DOI: 10.1002/jcb.240190202

No coin nor oath required. For personal study only.

✦ Synopsis

Peyton Rous, a great scientist and exemplar, did not only discover Rous sarcoma virus (RSV)-or "chicken tumor I virus" as he called it-which caused spindle-celled sarcomas in sensitive chickens. He also found other chicken tumor viruses, among them a virus from chicken tumor VII which contained true cartilage and bone. This virus produced osteochondromas in sensitive birds. Rous stated [ 11:

Thus the agent, when brought into contact with the connective tissue in voluntary muscle, produces not an ordinary spindle-celled sarcoma, but a growth that elaborates cartilage and finally bone-that such an agent should bring about a differentiation ordinarily foreign to the tissue is very remarkable.

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