Viruses and human disease

✍ Scribed by James H. Strauss, Ellen G. Strauss

• Publisher: AP
• Year: 2008
• Tongue: English
• Leaves: 476
• Edition: 2ed.
• Category: Library

✦ Synopsis

Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss' virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. * Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information * Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia. * Further reading sections at the end of each chapter make it easy find key references * World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text * A companion website features illustrations for use in class notes and presentations.

✦ Table of Contents

Viruses and Human Disease......Page 4
Copyright Page......Page 5
Table of Contents......Page 6
Preface to the Second Edition......Page 8
Introduction......Page 9
Classification of Viruses......Page 14
An Overview of the Replication Cycle of Viruses......Page 15
Effects of Virus Infection on the Host Cell......Page 37
Epidemiology: The Spread of Viruses from Person to Person......Page 39
Further Reading......Page 40
Helical Symmetry......Page 43
Icosahedral Symmetry......Page 44
Enveloped Viruses......Page 53
Assembly of Virions......Page 66
Stability of Virions......Page 69
Further Reading......Page 70
Family Picornaviridae......Page 71
Family Caliciviridae......Page 91
Family Hepeviridae......Page 94
Family Astroviridae......Page 95
Family Togaviridae......Page 97
Family Flaviviridae......Page 114
Family Coronaviridae......Page 132
Family Arteriviridae......Page 136
The Plus-Strand RNA Viruses of Plants......Page 138
Origin and Evolution of Plus-Strand RNA Viruses......Page 140
Further Reading......Page 142
Overview of the Minus-Strand RNA Viruses......Page 145
Family Rhabdoviridae......Page 149
Family Paramyxoviridae......Page 155
Family Filoviridae......Page 166
Family Bornaviridae......Page 169
Family Orthomyxoviridae......Page 170
Family Bunyaviridae......Page 183
Family Arenaviridae......Page 191
Evolution of Minus-Strand RNA Viruses......Page 196
Further Reading......Page 197
Overview of the Family Reoviridae......Page 201
Further Reading......Page 217
Introduction......Page 219
Family Retroviridae......Page 220
Family Hepadnaviridae......Page 257
Further Reading......Page 266
Introduction......Page 269
Family Poxviridae......Page 271
Family Herpesviridae......Page 284
Replication of Herpesviruses......Page 290
Family Adenoviridae......Page 303
Family Polyomaviridae......Page 310
Family Papillomaviridae......Page 316
Family Parvoviridae......Page 322
Torque Teno Virus: A Newly Described Human Virus......Page 328
Further Reading......Page 330
Bat-Associated Viruses......Page 333
Viruses Associated with Birds......Page 339
Viruses Associated with Primates......Page 344
Viruses Associated with Rodents......Page 349
Further Reading......Page 350
Defective Interfering Viruses......Page 353
Satellites and Satellite Viruses......Page 356
Viroids and Virusoids......Page 357
Hepatitis delta......Page 358
Prions and Prion Diseases......Page 365
Prions of Yeast......Page 375
Further Reading......Page 376
Adaptive Immune System......Page 377
Innate Immune System......Page 397
Viral Counterdefenses......Page 413
Interactions of Viruses with their Hosts......Page 426
Further Reading......Page 427
Virus Vector Systems......Page 431
Use of Viruses As Expression Vectors......Page 440
Gene Therapy......Page 445
Further Reading......Page 454
Appendix: References Used for Figures and Tables......Page 457
Index......Page 469