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Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia

✍ Scribed by Kirsten J Flynn; Gabrielle T Belz; John D Altman; Rafi Ahmed; David L Woodland; Peter C Doherty


Book ID
117722916
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
179 KB
Volume
8
Category
Article
ISSN
1074-7613

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## Abstract Activation of mature CD8^+^ T cells requires recognition, __via__ the T cell receptor (TCR), of peptide + MHC (pMHC) complexes with an avidity that exceeds a designated threshold. Multiple indicators of T cell avidity have been described that provide unique information on the characteri