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Virus-specific CD8 T cells: activation, differentiation and memory formation

✍ Scribed by MELANIE WIESEL; SENTA WALTON; KIRSTEN RICHTER; ANNETTE OXENIUS


Book ID
109343920
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
289 KB
Volume
117
Category
Article
ISSN
0365-5555

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Hepatitis C virus (HCV) causes chronic infection accompanied by a high risk of liver failure and hepatocellular carcinoma. CD8Ψ‰ T cell responses are important in the control of viremia. However, the T cell response in chronic infection is weak both in absolute numbers and in the range of epitopes ta