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Virus-induced diabetes mellitus: autoimmunity and polyendocrine disease prevented by immunosuppression

โœ Scribed by Onodera, Takashi; Ray, Usha R.; Melez, Kathleen A.; Suzuki, Hoshibumi; Toniolo, Antonio; Notkins, Abner Louis


Book ID
109726353
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
329 KB
Volume
297
Category
Article
ISSN
0028-0836

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In this study, we describe a radioimmunoassay to detect liver membrane binding antibodies. The assay was designed to exclude binding of aggregated IgG or immune complexes to Fc y receptors of hepatocytes. When this assay was applied to sera from 142 patients, antibodies were found in highest titer i