Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene

Inhibition of highly pathogenic avian H5

Inhibition of highly pathogenic avian H5N1 influenza virus propagation by RNA oligonucleotides targeting the PB2 gene in combination with celecoxib

✍ Yi Jin; Guozhong Zhang; Yanxin Hu; Meng Ding; Yi Li; Shanpin Cao; Jia Xue; Lun-Q 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB

## Abstract ## Background Highly pathogenic avian influenza virus H5N1 can cause acute respiratory infections with an uncontrolled virus‐induced cytokine storm in both poultry and humans. In view of the high mortality of H5N1 influenza virus infection, the development of novel broad‐spectrum proph