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Virulence-associated CRASP proteins of Borrelia burgdorferi bind distinct members of the human factor H protein family and extracellular matrix components

✍ Scribed by Teresia Hallström; Corinna Siegel; Christine Skerka; Volker Brade; Brian Stevenson; Reinhard Wallich; Peter Kraiczy; Peter Zipfel

Book ID: 116757131
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 88 KB
Volume: 45
Category: Article
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2008.08.215

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## Abstract The causative agents of Lyme disease, __Borrelia burgdorferi__ s.s., __B. garinii__, and __B. afzelii__, differ in their susceptibility to complement‐mediated lysis. This phenomenon apparently depends on the expression of proteins termed complement regulator‐acquiring surface proteins (