Virchow 2011 or How to ID(H) Human Glioblastoma

Delineation of Receptor-Ligand Interacti

Delineation of Receptor-Ligand Interactions at the Human Histamine H1 Receptor by a Combined Approach of Site-Directed Mutagenesis and Computational Techniques – or – How to Bind the H1 Receptor

✍ Aldo Jongejan; Rob Leurs 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB 👁 2 views

## Abstract Histamine H~1~ antagonists or “antihistamines” are one of the most prescribed drug families in Western countries. They exert their effect by binding to the histamine H~1~ receptor, a receptor belonging to the class of rhodopsin‐like G protein‐coupled receptors (GPCRs). In this review, t