Viral vector-mediated gene therapy for Parkinson's disease
β Scribed by Marina E. Emborg; Nicole Deglon; Liza Leventhal; Patrick Aebischer; Jeffrey H. Kordower
- Book ID
- 118629671
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 690 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1566-2772
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## Abstract The once fantastic theoretical concept that patients with Parkinson's disease (PD) would receive gene therapy in an attempt to alleviate their symptoms and potentially modify the course of their disease has become a reality. On the basis of positive preclinical data, four different gene
Parkinsonβs disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder ha