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Viral vector-based prime-boost immunization regimens: a possible involvement of T-cell competition

โœ Scribed by Wilschut, J; Daemen, T; de Mare, A; Lambeck, A J A; Regts, J; van Dam, G M; Nijman, H W; Snippe, H


Book ID
110040104
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
337 KB
Volume
15
Category
Article
ISSN
0969-7128

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## Abstract The immunogenic properties of plasmid DNA and recombinant adenovirus (Ad) encoding the carcinoembryonic antigen (CEA) were examined in mice by measuring both the amplitude and type of immune response, and the immunogenicity of codon usage optimized cDNA encoding CEA (CEAopt) was assesse