Viral thymidine kinase in essential for the spread of herpes simplex virus (HSV) induced zosteriform lesions in vivo
β Scribed by MJ Mulqueen; AM Watkins; PJ Dunford; P Wong Kai-In; G Thomas; RW Lambert; KEB Parkes; JH Merrett; SA Malcolm; NA Roberts; JA Martin
- Book ID
- 114145090
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 112 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0166-3542
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## Abstract To analyze the site of integration of the herpes simplex virus type 1 (HSVβ1) thymidine kinase (TK) gene in biochemically transformed human cells, TKβHeLaβ(BU25) cells were transformed to the TK^+^ phenotype by a cloned, 2 kbp Pvull fragment of HSVβ1 DNA. The transformed cells [HeLa(BU2