Viral infections and molecular mimicry in type 1 diabetes
โ Scribed by Coppieters, Ken T.; Wiberg, Anna; von Herrath, Matthias G.
- Book ID
- 119826616
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 180 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0365-5555
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## Abstract During the last decades, the incidence of type 1 diabetes (T1D) has increased significantly, reaching percentages of 3% annually worldwide. This increase suggests that besides genetical factors environmental perturbations (including viral infections) are also involved in the pathogenesi
## Abstract More recent evidence shows that viral infections can enhance as well as prevent type 1 diabetes in experimental animal models [Filippi and von Herrath, 2010]. Published findings clearly indicate that the replication levels of the virus [Tracy et al., 2010] as well as the timing of infec