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Viral glycoprotein metabolism as a target for antiviral substances

✍ Scribed by Klenk, Hans-Dieter; Schwarz, Ralph T.

Book ID: 121910680
Publisher: Elsevier Science
Year: 1982
Tongue: English
Weight: 844 KB
Volume: 2
Category: Article
ISSN: 0166-3542
DOI: 10.1016/0166-3542(82)90041-9

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## Abstract One of the three key enzymes encoded by the __pol__ gene of HIV is a __M__~r~ 32 000 protein called HIV integrase. This viral enzyme is involved in the integration of HIV DNA into host chromosomal DNA. There appears to be no functional equivalent of the enzyme in human cells. The bioche