Viral and host genetic factors influence encephalomyocarditis virus—induced polymyositis in adult mice

Genetic factors influence ethanol-induce

Genetic factors influence ethanol-induced uroporphyria in Hfe (—/—) mice

✍ Nadia Gorman; Heidi W. Trask; William J. Bement; Juliana G. Szakacs; George H. E 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 900 KB

Two major risk factors for porphyria cutanea tarda (PCT) are alcohol consumption and homozygosity for the C282Y mutation in the hereditary hemochromatosis gene (HFE). We recently described an animal model for alcohol-induced uroporphyria, using Hfe(-/-) mice. In the present study we show that this e