Vindesine/Cisplatin chemotherapy in relapsed or primarily resistant small-cell carcinoma of the lung
✍ Scribed by Niederle, N. ;Schütte, J. ;Krischke, W. ;Seeber, S. ;Schmidt, C. G.
- Book ID
- 105288687
- Publisher
- Springer-Verlag
- Year
- 1984
- Tongue
- English
- Weight
- 526 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1432-1440
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📜 SIMILAR VOLUMES
Twenty-nine patients with non-small cell lung cancer refractory to prior therapy were treated with either vindesine (VDS) alone (3 mg/m2 every week) or the combination of VDS plus cisplatin (DDP) (100 mg/m2 every 28 days). Serial blood and urine samples were collected to assess the pharmacokinetics
Twenty-five patients with measurable small cell lung cancer relapsing after first-line chemotherapy were treated with vindesine 3 mg/m2 IV on days 1 and 8 and hexamethylmelamine 100 mg/m2 PO on days 1-14, repeated every 3 weeks. Among 18 fully evaluable patients there was 1 partial remission lasting