✦ LIBER ✦

Vincristine polyneuropathy in man

✍ Scribed by M. R. Caccia; B. Comotti; E. Ubiali; A. Lucchetti

Publisher: Springer
Year: 1977
Tongue: English
Weight: 327 KB
Volume: 216
Category: Article
ISSN: 0340-5354
DOI: 10.1007/bf00312811

No coin nor oath required. For personal study only.

✦ Synopsis

A clinical and electrophysiological follow up study of 14 cases of hemopathic patients patients undergoing VCR therapy showed evidence that the drug has a direct action on the motor and sensory axon but not on the propagation velocity. Sensory nerves seem to be affected earlier and more than motor ones. Correlation was good between clinical and electrophysiological findings for both functions. The findings in man correspond with the animal data and therefore lead to the conclusion that VCR polyneuropathy is due to an involvement of the nerve axon.

📜 SIMILAR VOLUMES

The pharmacokinetics of vincristine in m

The pharmacokinetics of vincristine in man:

✍ H. W. Berg; Z. R. Desai; R. Wilson; G. Kennedy; J. M. Bridges; R. G. Shanks 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 421 KB

Heterozygous P0 deficiency protects mice

Heterozygous P0 deficiency protects mice from vincristine-induced polyneuropathy

✍ Nurcan Üçeyler; Igor Kobsar; Lydia Biko; Jochen Ulzheimer; S. Rock Levinson; Rud 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 404 KB

## Abstract Patients with hereditary neuropathies are more susceptible to vincristine (VIN)‐induced neuropathy than patients without this comorbidity. The heterozygous P0^+/–^ mouse is an animal model of a distinct form of inherited neuropathies. These mice produce only 50% of the major myelin prot

A novel transthyretin mutation V32A in a

A novel transthyretin mutation V32A in a Chinese man with late-onset amyloid polyneuropathy

✍ Emmanuel C. Pica; Zacharias Ad Pramono; Kamal K. Verma; Lai Poh San; Yee Woon Ch 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB

Polyneuropathy in lithium intoxication

✍ Geert Vanhooren; Ides Dehaene; Michel Van Zandycke; Frans Piessens; Vic Vandenbe 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 551 KB

Mandibular nerve involvement in diabetic

Mandibular nerve involvement in diabetic polyneuropathy and chronic inflammatory demyelinating polyneuropathy

✍ G. Cruccu; R. Agostino; M. Inghilleri; P. Innocenti; A. Romaniello; M. Manfredi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 2 views

Sensory complaints in the area of the mandible and mouth often escape notice or remain undiagnosed. Using electromyographic recording of the trigeminal reflexes and motor responses, we sought trigeminal dysfunction in 50 patients with peripheral neuropathy, and tried to gain pathophysiological infor

Alcoholic polyneuropathy

✍ Dr. Robert W. Shields Jr 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB