Video documented follow-up of liver transplantation in Wilson's disease with predominant neurological manifestation
✍ Scribed by Thorsten Suess; Martin Bokemeyer; Georg Schomerus; Frank Donnerstag; Michael Peter Manns; Juergen Klempnauer; Hans Kolbe; Karin Weissenborn
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 88 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
Wilson's disease (WD) is a rare autosomal‐recessive disorder of copper metabolism with predominantly hepatic and extrapyramidal motor symptoms. Copper chelating therapy has proven to be an effective treatment for WD. Yet, if conservative treatment fails, liver transplantation (LT) often is the only remaining therapeutic option. The indication for LT especially in patients with stable liver function but severe neurological manifestation is debated controversially. In this case report, we document the follow up of neurological symptoms in WD after LT for the first time on video. © 2007 Movement Disorder Society