Vibrational circular dichroism of polypeptides and proteins
β Scribed by Yasui, Sritana C. ;Keiderling, Timothy A.
- Book ID
- 105165361
- Publisher
- Springer-Verlag
- Year
- 1988
- Weight
- 161 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0344-838X
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## Synopsis Vibrational CD (VCD) of amide I and I1 vibrations of several a-helical polypeptides have been measured in solution. For the amide I1 as well as the amide I [previously published: Lal, B.B. & Nafie, L.A. (1982) Biopolymers 21, 21611 we find the VCD to be characteristic of the polypeptid
## Abstract Vibrational CD (VCD) of amides A, I, and II vibrations of a variety of polypeptide films have been measured. VCD of films of Ξ±βhelical and Ξ²βsheet structures are compared in the three regions. Reproducible spectra could only be obtained for thin films free of orientation dependence. The
We have measured vibrational CD spectra in the 3600-1250 cm-I region of two monodisperse, protected octapeptides, which form right-handed 3,,-helices in CDC13 solution. The spectra are similar in sign pattern to those obtained for right-handed a-helices in solution but are smaller in magnitude and,