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VH-mediated mechanisms in normal and neoplastic B Cell development

✍ Scribed by Leslie E. Silberstein; Sambasiva P. Rao

Book ID
105608324
Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
794 KB
Volume
17
Category
Article
ISSN
0257-277X

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## Abstract We show that major histocompatibility complex (MHC) class II molecules on B cells transmit signals which regulate adhesion in a negative manner. Engagement of MHC class II molecules with antibodies results in detachment of B cells previously bound to interferon‐γ‐activated human umbilic