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VH CDR3-dependent positive selection of murine VH12-expressing B cells in the neonate

✍ Scribed by Stephen H. Clarke; Suzanne K. McCray


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
848 KB
Volume
23
Category
Article
ISSN
0014-2980

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The majority of murine VH12-expressing B
✍ Jian Ye; Suzanne K. McCray; Stephen H. Clarke 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 996 KB

## Abstract We have previously demonstrated that at birth most productive (P) V~H~12 rearrangements in B10.H‐2^a^H‐4^b^p/Wts (2^a^4^b^) mice encode a ten‐amino acid CDR3, and that a significant fraction of the expected repertoire is absent. We have now examined the adult V~H~12 CDR3 repertoire invo