𝔖 Bobbio Scriptorium
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vestigial suppressor genes and resistance to aminopterin in Drosophila melanogaster

✍ Scribed by Bazin, C; Silber, J

Book ID
109859568
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
244 KB
Volume
69
Category
Article
ISSN
0018-067X

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The vestigial locus of Drosophila melano
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The vestigal (vg) gene encodes a nuclear protein which plays a major role in the formation of the wing of Drosophila. Resistance or sensitivity to aminopterin, an inhibitor of the dihydrofolate reductase enzyme in D. melanogaster, seems to be associated with a specific alteration in vg gene function

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The aim of our work was to compare the mechanisms of resistance to aminopterin, inhibitor of the dihydrofolate reductase enzyme, between different Drosophila species and those described for cultured cells. Moreover we compared the systematic species divisions based on morphological traits and those