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Verzögerte Implantation und frühembryonale Keimschäden bei der Maus nach Applikation des PCB: 2,2′-Dichlorbiphenyl

✍ Scribed by Peter Török


Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
940 KB
Volume
40
Category
Article
ISSN
0340-5761

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✦ Synopsis


Pregnant mice administered per os during the days 1--3 (plug day = day 0) post conception (p.c.) with 375 mg 2,2'-dichlorobiphenyl/kilograms/day revealed on day 18 p.c. increased number of resorptions and doses up from 500 milligrams/kilograms/day led to a substantial retardation of the prenatal development. Based on the investigations during the early development it is concluded, that retardation of the fetus is caused by a delayed implantation. It is assumed, that increased resorption is due to kyematopathies detected during the periimplantation period.