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VERY-LOW-DOSE CYTARABINE FOR MYELODYSPLASTIC SYNDROMES AND ACUTE MYELOID LEUKAEMIA IN THE ELDERLY

โœ Scribed by Worsley, Alison; Mufti, G.J.; Copplestone, J.A.; Oscier, D.G.; Hamblin, T.J.

Book ID
123214979
Publisher
The Lancet
Year
1986
Tongue
English
Weight
145 KB
Volume
327
Category
Article
ISSN
0140-6736

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Acute myeloid leukaemia (AML) secondary to myelodysplastic syndrome (MDS) is characterized by poor prognosis, namely in older patients. The combination of fludarabine (F) with cytarabine (ARA-C) AE G-CSF was proven as effective in patients with poor risk AML. The efficacy and toxicity of a regimen i